Anaemia (cancer-treatment induced) - erythropoietin (alpha and beta) and darbepoetin - Technology Appraisal TA142 (28th May 2008)
Erythropoietin analogues with iron injections are recommended as a possible treatment for anaemia caused by cancer treatment only in: women receiving platinum-based chemotherapy for cancer of the ovaries who have a blood haemoglobin level of 8 g/100 ml or lower; people who have very severe anaemia and cannot receive blood transfusions.
Click here for Guidance
Click here for Quick Reference Guide
Click here for Understanding NICE Guidance
Click here for Costing statement
Click here for Audit support
Ankylosing spondylitis - adalimumab, etanercept and infliximab - Technology Appraisal TA143 (28th May 2008)
Adalimumab or etanercept are recommended as possible treatments for people with severe ankylosing spondylitis who: have active spinal disease as assessed on two separate occasions 12 weeks apart, and have tried at least two non-steroidal anti-inflammatory drugs (NSAIDs) but they have not worked.
Click here for Guidance
Click here for Quick Reference Guide
Click here for Understanding NICE Guidance
Click here for Cost Template
Click here for Audit Support
Canaloplasty for primary open-angle glaucoma - Intervention Procedure Guidance IP260 (28th May 2008)
Primary open angle glaucoma is a condition associated with a long-term increase of pressure within the eye. It may gradually lead to permanent loss of sight because of damage to the nerve that connects the eye to the brain (optic nerve), which is essential for sight. Canaloplasty involves widening the main drainage canal in the eye to help prevent the build up of fluid. The drainage canal is situated within the angle between the iris (the coloured part of the eye) and cornea (the transparent outer coating of the eye). A tiny tube is inserted into the canal and a thick fluid (viscoelastic) is injected to open it up. The tube is then removed and a stitch is placed within the canal to keep it open. The aim is to restore the eye’s natural drainage system and reduce pressure within the eye.
Click here for Guidance
Click here for Understanding NICE Guidance
Click here for Consultation Comments
Diabetes Type 2 (update) - Clinical Guideline CG66 (28th May 2008)
This guidance is about the care and treatment of people with type 2 diabetes in the NHS in England and Wales. It covers: the monitoring of glucose, lipid (blood cholesterol and fat) and blood pressure levels; diabetes education programmes; dietary advice. The use of medications to: control blood glucose; prevent vascular (blood vessel) disease; reduce blood pressure; improve lipid levels. The detection and ongoing management (with referral to a specialist if necessary) of: eye disease; kidney disease; nerve damage and nerve pain; depression.
Click here for Full Guideline
Click here for NICE Guidance
Click here for Quick Reference Guide
Click here for Appendices
Click here for Understanding NICE Guidance
Click here for Consultation Table
Click here for Costing Statement
Endoaortic balloon occlusion for cardiac surgery - Intervention Procedure Guidance IPG261 (28th May 2008)
During major heart surgery, the flow of blood through the heart needs to be stopped temporarily. In endoaortic balloon occlusion, a flexible tube (catheter) with a balloon attached to its tip is inserted into an artery in the groin (femoral artery) and threaded up to the heart. When the catheter is in the correct position in the heart, the balloon is filled with saline. As the balloon expands it blocks the aorta, which is the largest artery in the body. With the aorta blocked, the heart surgery can be performed. After heart surgery, the balloon and catheter are removed and the blood flow is restored.
Click here for Guidance
Click here for Understanding NICE Guidance
Click here for Consultation Comments
Lipid modification - Clinical Guideline CG67 (28th May 2008)
This guideline covers: Adults at higher risk of heart disease, stroke or peripheral arterial disease (cardiovascular disease). Risk of cardiovascular disease increases with age, as well as in people who smoke or who have high blood pressure or high cholesterol. People with heart disease in the family or men with a South Asian (for example, Indian, Pakistani or Bangladeshi) background are also at higher risk; People who have already had a heart attack, stroke or 'mini-stroke' (transient ischaemic attack or TIA); People who have angina or some other forms of cardiovascular disease.
Click here for NICE Guideline
Click here for Full Guidance
Click here for Guidance Appendices A-C
Click here for Guidance Appendix D
Click here for Guidance Appendices E-J
Click here for Guidance Appendix K
Click here for Guidance Appendix L
Click here for Quick Reference Guide
Click here for Understanding NICE Guidance
Click here for Costing Report
Click here for Costing Template
Promoting Physical Activity in the Workplace - Public Health Intervention Guidance PH13 (28th May 2008)
This guidance is for employers and professionals in small, medium and large organisations who have a direct or indirect role in, and responsibility for, improving health in the workplace. This includes those working in the NHS, local authorities and the wider public, voluntary, community and private sectors, especially those working in human resources or occupational health. It will also be of interest to employees, trades union representatives and members of the public. The guidance complements and supports, but does not replace, NICE guidance on: physical activity and the environment, workplace smoking and obesity.
Click here for Full Guidance
Click here for Quick Reference Guide
Click here for Business Case
Single-incision sub-urethral short tape insertion for stress urinary incontinence in women - Intervention Procedure Guidance IPG262 (28th May 2008)
Stress urinary incontinence is the involuntary leakage of urine during exercise or certain movements such as coughing, sneezing and laughing. It is usually due to weak or damaged muscles and connective tissues in the pelvic floor. Single incision sub-urethral short tape insertion involves the insertion of a short synthetic tape under the urethra, through an incision in the vagina. The tape aims to support the urethra (the passage through which urine leaves the bladder), to reduce the chance of urine leaking when the bladder is put under pressure.
Click here for Guidance
Click here for Understanding NICE Guidance
Click here for Consultation Comments
Metastic spinal cord compression: consultation (23rd May 2008)
A clinical practice guideline on Metastatic spinal cord compression is being developed for use in the NHS in England, Wales and Northern Ireland. Registered stakeholders for this guideline are invited to comment on the provisional recommendations via this website. Closing date for comments is 18th July 2008.
Click here for Draft Full Guideline
Click here for Draft NICE Guideline
Click here for Full Evidence Review
Click here for Comments Proforma
Hyperuricaemia - Febuxostat: appraisal consultation document (28th May 2008)
The Department of Health has asked the National Institute for Health and Clinical Excellence (NICE or the Institute) to conduct a single technology appraisal (STA) of febuxostat for the management of hyperuricaemia in patients with gout and provide guidance on its use to the NHS in England and Wales. The Appraisal Committee has had its first meeting to consider both the evidence submitted by the manufacturer and the views put forward by non-manufacturer consultees and commentators, and by the clinical specialist and patient expert representatives nominated for this appraisal by non-manufacturer consultees and commentators. The Committee has developed preliminary recommendations on the use of febuxostat. Closing date for comments is 17th June 2008.
Click here for the Consultation
Erythropoietin analogues with iron injections are recommended as a possible treatment for anaemia caused by cancer treatment only in: women receiving platinum-based chemotherapy for cancer of the ovaries who have a blood haemoglobin level of 8 g/100 ml or lower; people who have very severe anaemia and cannot receive blood transfusions.
Click here for Guidance
Click here for Quick Reference Guide
Click here for Understanding NICE Guidance
Click here for Costing statement
Click here for Audit support
Ankylosing spondylitis - adalimumab, etanercept and infliximab - Technology Appraisal TA143 (28th May 2008)
Adalimumab or etanercept are recommended as possible treatments for people with severe ankylosing spondylitis who: have active spinal disease as assessed on two separate occasions 12 weeks apart, and have tried at least two non-steroidal anti-inflammatory drugs (NSAIDs) but they have not worked.
Click here for Guidance
Click here for Quick Reference Guide
Click here for Understanding NICE Guidance
Click here for Cost Template
Click here for Audit Support
Canaloplasty for primary open-angle glaucoma - Intervention Procedure Guidance IP260 (28th May 2008)
Primary open angle glaucoma is a condition associated with a long-term increase of pressure within the eye. It may gradually lead to permanent loss of sight because of damage to the nerve that connects the eye to the brain (optic nerve), which is essential for sight. Canaloplasty involves widening the main drainage canal in the eye to help prevent the build up of fluid. The drainage canal is situated within the angle between the iris (the coloured part of the eye) and cornea (the transparent outer coating of the eye). A tiny tube is inserted into the canal and a thick fluid (viscoelastic) is injected to open it up. The tube is then removed and a stitch is placed within the canal to keep it open. The aim is to restore the eye’s natural drainage system and reduce pressure within the eye.
Click here for Guidance
Click here for Understanding NICE Guidance
Click here for Consultation Comments
Diabetes Type 2 (update) - Clinical Guideline CG66 (28th May 2008)
This guidance is about the care and treatment of people with type 2 diabetes in the NHS in England and Wales. It covers: the monitoring of glucose, lipid (blood cholesterol and fat) and blood pressure levels; diabetes education programmes; dietary advice. The use of medications to: control blood glucose; prevent vascular (blood vessel) disease; reduce blood pressure; improve lipid levels. The detection and ongoing management (with referral to a specialist if necessary) of: eye disease; kidney disease; nerve damage and nerve pain; depression.
Click here for Full Guideline
Click here for NICE Guidance
Click here for Quick Reference Guide
Click here for Appendices
Click here for Understanding NICE Guidance
Click here for Consultation Table
Click here for Costing Statement
Endoaortic balloon occlusion for cardiac surgery - Intervention Procedure Guidance IPG261 (28th May 2008)
During major heart surgery, the flow of blood through the heart needs to be stopped temporarily. In endoaortic balloon occlusion, a flexible tube (catheter) with a balloon attached to its tip is inserted into an artery in the groin (femoral artery) and threaded up to the heart. When the catheter is in the correct position in the heart, the balloon is filled with saline. As the balloon expands it blocks the aorta, which is the largest artery in the body. With the aorta blocked, the heart surgery can be performed. After heart surgery, the balloon and catheter are removed and the blood flow is restored.
Click here for Guidance
Click here for Understanding NICE Guidance
Click here for Consultation Comments
Lipid modification - Clinical Guideline CG67 (28th May 2008)
This guideline covers: Adults at higher risk of heart disease, stroke or peripheral arterial disease (cardiovascular disease). Risk of cardiovascular disease increases with age, as well as in people who smoke or who have high blood pressure or high cholesterol. People with heart disease in the family or men with a South Asian (for example, Indian, Pakistani or Bangladeshi) background are also at higher risk; People who have already had a heart attack, stroke or 'mini-stroke' (transient ischaemic attack or TIA); People who have angina or some other forms of cardiovascular disease.
Click here for NICE Guideline
Click here for Full Guidance
Click here for Guidance Appendices A-C
Click here for Guidance Appendix D
Click here for Guidance Appendices E-J
Click here for Guidance Appendix K
Click here for Guidance Appendix L
Click here for Quick Reference Guide
Click here for Understanding NICE Guidance
Click here for Costing Report
Click here for Costing Template
Promoting Physical Activity in the Workplace - Public Health Intervention Guidance PH13 (28th May 2008)
This guidance is for employers and professionals in small, medium and large organisations who have a direct or indirect role in, and responsibility for, improving health in the workplace. This includes those working in the NHS, local authorities and the wider public, voluntary, community and private sectors, especially those working in human resources or occupational health. It will also be of interest to employees, trades union representatives and members of the public. The guidance complements and supports, but does not replace, NICE guidance on: physical activity and the environment, workplace smoking and obesity.
Click here for Full Guidance
Click here for Quick Reference Guide
Click here for Business Case
Single-incision sub-urethral short tape insertion for stress urinary incontinence in women - Intervention Procedure Guidance IPG262 (28th May 2008)
Stress urinary incontinence is the involuntary leakage of urine during exercise or certain movements such as coughing, sneezing and laughing. It is usually due to weak or damaged muscles and connective tissues in the pelvic floor. Single incision sub-urethral short tape insertion involves the insertion of a short synthetic tape under the urethra, through an incision in the vagina. The tape aims to support the urethra (the passage through which urine leaves the bladder), to reduce the chance of urine leaking when the bladder is put under pressure.
Click here for Guidance
Click here for Understanding NICE Guidance
Click here for Consultation Comments
Metastic spinal cord compression: consultation (23rd May 2008)
A clinical practice guideline on Metastatic spinal cord compression is being developed for use in the NHS in England, Wales and Northern Ireland. Registered stakeholders for this guideline are invited to comment on the provisional recommendations via this website. Closing date for comments is 18th July 2008.
Click here for Draft Full Guideline
Click here for Draft NICE Guideline
Click here for Full Evidence Review
Click here for Comments Proforma
Hyperuricaemia - Febuxostat: appraisal consultation document (28th May 2008)
The Department of Health has asked the National Institute for Health and Clinical Excellence (NICE or the Institute) to conduct a single technology appraisal (STA) of febuxostat for the management of hyperuricaemia in patients with gout and provide guidance on its use to the NHS in England and Wales. The Appraisal Committee has had its first meeting to consider both the evidence submitted by the manufacturer and the views put forward by non-manufacturer consultees and commentators, and by the clinical specialist and patient expert representatives nominated for this appraisal by non-manufacturer consultees and commentators. The Committee has developed preliminary recommendations on the use of febuxostat. Closing date for comments is 17th June 2008.
Click here for the Consultation
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