New database to inform prioritisation of European cancer research (20th October 2009)
A 'Database of Cancer Uncertainties' (DoCU) went live on the NICE website today. The database will collate details of the major gaps in evidence which are identified during guidance development. These evidence gaps can then be promoted as research priorities to prospective research funders.
The database has been developed as a pilot project by NICE, as part of the CoCanCPG (Coordination of Cancer Clinical Practice Guidelines in Europe). CoCanCPG is a consortium of 16 institutional partners from 11 countries.
Database
A 'Database of Cancer Uncertainties' (DoCU) went live on the NICE website today. The database will collate details of the major gaps in evidence which are identified during guidance development. These evidence gaps can then be promoted as research priorities to prospective research funders.
The database has been developed as a pilot project by NICE, as part of the CoCanCPG (Coordination of Cancer Clinical Practice Guidelines in Europe). CoCanCPG is a consortium of 16 institutional partners from 11 countries.
Database
What do you think about the NICE website? (27th October 2009)
As part of their continuing programme of evaluation and development, NICE are currently consulting with health service and local government professionals, patients, carers and the public to find out what they think of the NICE website.
The survey is available online until 15th November 2009.
Survey
As part of their continuing programme of evaluation and development, NICE are currently consulting with health service and local government professionals, patients, carers and the public to find out what they think of the NICE website.
The survey is available online until 15th November 2009.
Survey
Neuropathic pain - pharmacological management: guideline consultation (14th October 2009)
A clinical practice guideline on Neuropathic pain is being developed for use in the NHS in England, Wales and Northern Ireland. Registered stakeholders for this guideline are invited to comment on the provisional recommendations via this website.
Closing date for comments is 11th November 2009
Consultation
Prevention of cardiovascular disease: additional evidence consultation (14th October 2009)
NICE was asked by the Department of Health (DH) to develop public health programme guidance on preventing cardiovascular disease (CVD) in different populations.
All registered stakeholders are now invited to comment on the economic analysis and additional evidence that has been assembled to inform the development of this guidance. This will be used by the Programme Development Group (PDG) to develop recommendations.
Closing date for comments is 16th November 2009.
Consultation
NICE was asked by the Department of Health (DH) to develop public health programme guidance on preventing cardiovascular disease (CVD) in different populations.
All registered stakeholders are now invited to comment on the economic analysis and additional evidence that has been assembled to inform the development of this guidance. This will be used by the Programme Development Group (PDG) to develop recommendations.
Closing date for comments is 16th November 2009.
Consultation
Prevention of cardiovascular disease: consultation on the draft guidance (15th October 2009)
NICE are consulting on the draft guidance ‘prevention of cardiovascular disease at the population level’. In particular, they are interested in the views of stakeholders on recommendations 3, 4 and 5 (on salt, saturated fats and trans fats). They are interested in views on:
Consultation
NICE are consulting on the draft guidance ‘prevention of cardiovascular disease at the population level’. In particular, they are interested in the views of stakeholders on recommendations 3, 4 and 5 (on salt, saturated fats and trans fats). They are interested in views on:
- Whether a figure for a lower target for salt intake could or should be identified at this stage
- Whether an even lower saturated fat intake is achievable
- The potential impact of a ban on industrial trans fats on cardiovascular disease in general and particularly the potential effects on existing inequalities in health.
Consultation
Rheumatoid arthritis - certolizumab pegol: appraisal consultation (20th October 2009)
This appraisal consultation on Rheumatoid arthritis - certolizumab pegol, is open for comments until 10th November 2009. All registered stakeholders are invited to comment.
Consultation
This appraisal consultation on Rheumatoid arthritis - certolizumab pegol, is open for comments until 10th November 2009. All registered stakeholders are invited to comment.
Consultation
Breast cancer (advanced or metastatic) - lapatinib: appraisal consultation document (21st October 2009)
The Department of Health and the Welsh Assembly Government have asked the National Institute for Health and Clinical Excellence (NICE) to produce guidance on using lapatinib for the treatment of women with previously treated advanced or metastatic breast cancer in the NHS in England and Wales. The Appraisal Committee has considered the evidence submitted by the manufacturer and the views of non-manufacturer consultees and commentators, and clinical specialists and patient experts.
Closing date for comments is 11th November 2009.
Consultation
The Department of Health and the Welsh Assembly Government have asked the National Institute for Health and Clinical Excellence (NICE) to produce guidance on using lapatinib for the treatment of women with previously treated advanced or metastatic breast cancer in the NHS in England and Wales. The Appraisal Committee has considered the evidence submitted by the manufacturer and the views of non-manufacturer consultees and commentators, and clinical specialists and patient experts.
Closing date for comments is 11th November 2009.
Consultation
Cytoreduction surgery followed by hyperthermic intraoperative peritoneal chemotherapy for peritoneal carcinomatosis (interventional procedures consultation) (21st October 2009)
The National Institute for Health and Clinical Excellence (NICE) is examining cytoreduction surgery followed by hyperthermic intraoperative peritoneal chemotherapy for peritoneal carcinomatosis and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. NICE’s Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about cytoreduction surgery followed by hyperthermic intraoperative peritoneal chemotherapy for peritoneal carcinomatosis.
Closing date for comments is 18th November 2009.
Consultation
The National Institute for Health and Clinical Excellence (NICE) is examining cytoreduction surgery followed by hyperthermic intraoperative peritoneal chemotherapy for peritoneal carcinomatosis and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. NICE’s Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about cytoreduction surgery followed by hyperthermic intraoperative peritoneal chemotherapy for peritoneal carcinomatosis.
Closing date for comments is 18th November 2009.
Consultation
Therapeutic endoscopic division of epidural adhesions (interventional procedures consultation) (21st October 2009)
The National Institute for Health and Clinical Excellence (NICE) is examining therapeutic endoscopic division of epidural adhesions and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. NICE’s Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about therapeutic endoscopic division of epidural adhesions.
Closing date for comments is 18th November 2009.
Consultation
The National Institute for Health and Clinical Excellence (NICE) is examining therapeutic endoscopic division of epidural adhesions and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. NICE’s Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about therapeutic endoscopic division of epidural adhesions.
Closing date for comments is 18th November 2009.
Consultation
Surgical correction of hallux valgus using minimal access techniques (interventional procedures consultation) (21st October 2009)
Hallux valgus is a deformity of the big toe. The big toe tilts outwards, crowding the smaller toes, and a bony lump (called a bunion) appears on the inside of the foot.
The National Institute for Health and Clinical Excellence (NICE) is examining surgical correction of hallux valgus using minimal access techniques and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. NICE’s Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about surgical correction of hallux valgus using minimal access techniques.
Closing date for comments is 18th November 2009.
Consultation
Hallux valgus is a deformity of the big toe. The big toe tilts outwards, crowding the smaller toes, and a bony lump (called a bunion) appears on the inside of the foot.
The National Institute for Health and Clinical Excellence (NICE) is examining surgical correction of hallux valgus using minimal access techniques and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. NICE’s Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about surgical correction of hallux valgus using minimal access techniques.
Closing date for comments is 18th November 2009.
Consultation
Selective internal radiation therapy for colorectal metastases in the liver (interventional procedures consultation) (21st October 2009)
Colorectal liver metastasis is cancer that has spread to the liver from the bowel. Selective internal radiation therapy (known as SIRT) uses radiation put into the patient’s liver to kill the cancer cells. Tiny radioactive ‘beads’ are injected into the artery that supplies blood to the liver (the hepatic artery). The beads become trapped (embolise) in the tiny blood vessels surrounding the cancer, releasing radiation directly onto it. The treatment may be repeated.
The National Institute for Health and Clinical Excellence (NICE) is examining selective internal radiation therapy for colorectal metastases in the liver and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. NICE’s Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about selective internal radiation therapy for colorectal metastases in the liver.
Closing date for comments is 18th November 2009.
Consultation
Colorectal liver metastasis is cancer that has spread to the liver from the bowel. Selective internal radiation therapy (known as SIRT) uses radiation put into the patient’s liver to kill the cancer cells. Tiny radioactive ‘beads’ are injected into the artery that supplies blood to the liver (the hepatic artery). The beads become trapped (embolise) in the tiny blood vessels surrounding the cancer, releasing radiation directly onto it. The treatment may be repeated.
The National Institute for Health and Clinical Excellence (NICE) is examining selective internal radiation therapy for colorectal metastases in the liver and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. NICE’s Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about selective internal radiation therapy for colorectal metastases in the liver.
Closing date for comments is 18th November 2009.
Consultation
Prosthetic intervertebral disc replacement in the cervical spine (interventional procedures consultation)(21st October 2009)
Bulging of a disc (called herniation) in the neck occurs when one or more of the spinal discs between the bones in the neck bursts and pushes against the spinal cord or nerve roots that run through the backbone. This herniation can cause pain in the neck, or pain, weakness and numbness in the arms and legs.
This procedure involves replacing damaged discs in the neck with artificial ones designed to act like natural neck discs.
The National Institute for Health and Clinical Excellence (NICE) is examining prosthetic intervertebral disc replacement in the cervical spine and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. NICE’s Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about prosthetic intervertebral disc replacement in the cervical spine.
Closing date for comments is 18th November 2009.
Consultation
Bulging of a disc (called herniation) in the neck occurs when one or more of the spinal discs between the bones in the neck bursts and pushes against the spinal cord or nerve roots that run through the backbone. This herniation can cause pain in the neck, or pain, weakness and numbness in the arms and legs.
This procedure involves replacing damaged discs in the neck with artificial ones designed to act like natural neck discs.
The National Institute for Health and Clinical Excellence (NICE) is examining prosthetic intervertebral disc replacement in the cervical spine and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. NICE’s Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about prosthetic intervertebral disc replacement in the cervical spine.
Closing date for comments is 18th November 2009.
Consultation
Venous thromboembolism - reducing the risk: pre-publication check (22nd October 2009)
Following two consultation periods on the provisional recommendations, the National Clinical Guidelines Centre for Acute and Chronic Conditions (NCGC) and the Guideline Development Group (GDG) for Venous thromboembolism – reducing the risk, have considered and responded to stakeholder comments and amended the draft guideline.
The revised full guideline is now available on the web for a pre-publication check of factual errors. This is still draft guidance and has not been sent out to the NHS. The pre-publication check is not an additional consultation or an opportunity to reopen arguments and issues highlighted during consultation on the draft guidelines. The GDG will already have considered these issues in forming the recommendations contained in the draft for the pre-publication check.
Registered stakeholders for this guideline are invited to report any factual errors in the guideline by 11th November 2009.
Pre-publication check
Following two consultation periods on the provisional recommendations, the National Clinical Guidelines Centre for Acute and Chronic Conditions (NCGC) and the Guideline Development Group (GDG) for Venous thromboembolism – reducing the risk, have considered and responded to stakeholder comments and amended the draft guideline.
The revised full guideline is now available on the web for a pre-publication check of factual errors. This is still draft guidance and has not been sent out to the NHS. The pre-publication check is not an additional consultation or an opportunity to reopen arguments and issues highlighted during consultation on the draft guidelines. The GDG will already have considered these issues in forming the recommendations contained in the draft for the pre-publication check.
Registered stakeholders for this guideline are invited to report any factual errors in the guideline by 11th November 2009.
Pre-publication check
Weight management in pregnancy: consultation on the evidence (22nd October 2009)
NICE was asked by the Department of Health (DH) to develop guidance on ‘Dietary interventions and physical activity interventions for weight management in pregnancy’.
All registered stakeholders are now invited to comment on the evidence that has been assembled to inform the development of this guidance. This evidence will be used by the Public Health Interventions Advisory Committee (PHIAC) to develop draft recommendations. The evidence comprises a review of effectiveness an economic analysis.
Closing date for comments is 19th November 2009.
Consultation
NICE was asked by the Department of Health (DH) to develop guidance on ‘Dietary interventions and physical activity interventions for weight management in pregnancy’.
All registered stakeholders are now invited to comment on the evidence that has been assembled to inform the development of this guidance. This evidence will be used by the Public Health Interventions Advisory Committee (PHIAC) to develop draft recommendations. The evidence comprises a review of effectiveness an economic analysis.
Closing date for comments is 19th November 2009.
Consultation
Bacterial meningitis and meningococcal septicaemia in children: guideline consultation (22nd October 2009)
A clinical practice guideline on Bacterial meningitis and meningococcal septicaemia in children is being developed for use in the NHS in England, Wales and Northern Ireland. Registered stakeholders for this guideline are invited to comment on the provisional recommendations.
Closing date for comments is 17th December 2009.
Consultation
A clinical practice guideline on Bacterial meningitis and meningococcal septicaemia in children is being developed for use in the NHS in England, Wales and Northern Ireland. Registered stakeholders for this guideline are invited to comment on the provisional recommendations.
Closing date for comments is 17th December 2009.
Consultation
Strategies to prevent unintentional injuries among under 15s: consultation on the evidence (26th October 2009)
NICE was asked by the Department of Health (DH) to ‘Prepare public health programme guidance on the prevention of unintentional injury in children under 15’.
All registered stakeholders are now invited to comment on the evidence that has been assembled to inform the development of this guidance. This evidence is used by the Programme Development Group (PDG) to develop draft recommendations.
Closing date for comments is 23rd November 2009.
Consultation
NICE was asked by the Department of Health (DH) to ‘Prepare public health programme guidance on the prevention of unintentional injury in children under 15’.
All registered stakeholders are now invited to comment on the evidence that has been assembled to inform the development of this guidance. This evidence is used by the Programme Development Group (PDG) to develop draft recommendations.
Closing date for comments is 23rd November 2009.
Consultation
Technology Appraisal TA182. Prasugrel for the treatment of acute coronary syndromes with percutaneous coronary intervention (28th October 2009)
Prasugrel in combination with aspirin is recommended as an option for preventing blockages in the arteries of people with acute coronary syndromes who are having a treatment called percutaneous coronary intervention only when:
Technology Appraisal TA183. Topotecan for the treatment of recurrent carcinoma of the cervix (28th October 2009)
Topotecan in combination with cisplatin is recommended as a possible treatment for women with recurrent or stage IVB cervical cancer only if they have not received cisplatin before. Healthcare professionals should not stop prescribing topotecan for women who have received cisplatin before and who were already taking topotecan with cisplatin when the guidance was issued. These women should be able to carry on taking topotecan until they and their healthcare professionals decide that it is the right time to stop treatment.
Guideline
Clinical Guideline CG90. Depression: the treatment and management of depression in adults (update) (28th October 2009)
This guideline is published alongside ‘Depression in adults with a chronic physical health problem: treatment and management’ (NICE clinical guideline 91), which makes recommendations on the identification, treatment and management of depression in adults aged 18 years and older who also have a chronic physical health problem.
Guideline
Clinical Guideline CG91. The treatment and management of depression in adults with chronic physical health problems (partial update of CG23)
This guideline is published alongside ‘Depression: the treatment and management of depression in adults (update)’ (NICE clinical guideline 90), which makes recommendations on the identification, treatment and management of depression in adults aged 18 years and older, in primary and secondary care.
This guideline (and CG90) update recommendations made in NICE technology appraisal guidance 97 for the treatment of depression only. The guidance in TA97 remains unchanged for the use of CCBT in the treatment of panic and phobia and obsessive compulsive disorder.
Guideline
Prasugrel in combination with aspirin is recommended as an option for preventing blockages in the arteries of people with acute coronary syndromes who are having a treatment called percutaneous coronary intervention only when:
- immediate percutaneous coronary intervention is necessary to treat an ST-segment-elevation myocardial infarction (a type of heart attack) or
- a blood clot has blocked a stent (a small mesh-like tube inserted into an artery to keep it open) during treatment with a drug called clopidogrel or
- the patient has diabetes mellitus.
Technology Appraisal TA183. Topotecan for the treatment of recurrent carcinoma of the cervix (28th October 2009)
Topotecan in combination with cisplatin is recommended as a possible treatment for women with recurrent or stage IVB cervical cancer only if they have not received cisplatin before. Healthcare professionals should not stop prescribing topotecan for women who have received cisplatin before and who were already taking topotecan with cisplatin when the guidance was issued. These women should be able to carry on taking topotecan until they and their healthcare professionals decide that it is the right time to stop treatment.
Guideline
Clinical Guideline CG90. Depression: the treatment and management of depression in adults (update) (28th October 2009)
This guideline is published alongside ‘Depression in adults with a chronic physical health problem: treatment and management’ (NICE clinical guideline 91), which makes recommendations on the identification, treatment and management of depression in adults aged 18 years and older who also have a chronic physical health problem.
Guideline
Clinical Guideline CG91. The treatment and management of depression in adults with chronic physical health problems (partial update of CG23)
This guideline is published alongside ‘Depression: the treatment and management of depression in adults (update)’ (NICE clinical guideline 90), which makes recommendations on the identification, treatment and management of depression in adults aged 18 years and older, in primary and secondary care.
This guideline (and CG90) update recommendations made in NICE technology appraisal guidance 97 for the treatment of depression only. The guidance in TA97 remains unchanged for the use of CCBT in the treatment of panic and phobia and obsessive compulsive disorder.
Guideline
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