PATIENT SAFETY

Organisational Patient Safety Incident Reports (7th October 2009)
The National Patient Safety Agency (NPSA) today publishes Organisational Patient Safety Incident Reports for each NHS trust or local health board across England and Wales.

The Organisational Patient Safety Incident Reports summarise incidents reported by frontline NHS staff that have occurred between October 2008 and March 2009, and reported to the NPSA by 30 June 2009.
News
Reports

Improving Patient Safety: Risk Management for Maternity and Gynaecology (Clinical Governance Advice 2) (9th October 2009)
This is the third edition of this guidance. The original edition, entitled Clinical Risk Management for Obstetricians and Gynaecologists, was published in January 2001 and revised in 2005 under the title Improving Patient Safety: Risk Management for Maternity and Gynaecology.
Guidance

The Government response to the Health Select Committee Report 'Patient Safety' (13th October 2009)
This Command Paper sets out the Government's response to the House of Commons Health Select Committee's Report on Patient Safety.
Report

NICE

Soft tissue sarcoma - trabectedin: appraisal consultation (29th June 2009)
The Department of Health has asked the National Institute for Health and Clinical Excellence (NICE) to produce guidance on using trabectedin in the NHS in England and Wales. The Appraisal Committee has considered the evidence submitted by the manufacturer and the views of non-manufacturer consultees and commentators, and clinical specialists and patient experts. Closing date for comments is 21st July 2009.
Consultation

Preventing unintentional road injuries among under 15s: road design - evidence consultation (30th June 2009)
NICE was asked by the Department of Health (DH) to develop ‘Produce guidance on public health interventions to reduce accidental injuries to persons under the age of 15 on the road’. All registered stakeholders are now invited to comment on the evidence that has been assembled to inform the development of this guidance. This evidence will be used by the Public Health Interventions Advisory Committee (PHIAC) to develop draft recommendations. The evidence comprises a review of effectiveness and cost effectiveness, a review of qualitative evidence and an economic analysis. Closing date for comments is 28th July 2009.
Consultation

Percutaneous intradiscal electrothermal therapy for low back pain (interventional procedures second consultation) (30th June 2009)
The National Institute for Health and Clinical Excellence (NICE) is examining percutaneous intradiscal electrothermal therapy for low back pain and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. NICE’s Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about percutaneous intradiscal electrothermal therapy for low back pain. Closing date for comments is 28th July 2009.
Consultation

Bronchoscopic lung volume reduction with an airway valve for advanced emphysema (interventional procedures consultation) (30th June 2009)
The National Institute for Health and Clinical Excellence (NICE) is examining bronchoscopic lung volume reduction with airway valves for advanced emphysema and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. NICE’s Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about bronchoscopic lung volume reduction with airway valves for advanced emphysema.

This document summarises the procedure and sets out the provisional recommendations made by the Advisory Committee. Closing date for comments is 28th July 2009.
Consultation

Negative pressure wound therapy for the abdomen (interventional procedures consultation) (30th June 2009)
The National Institute for Health and Clinical Excellence (NICE) is examining negative pressure wound therapy for the open abdomen and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. NICE’s Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about negative pressure wound therapy for the open abdomen.

This document summarises the procedure and sets out the provisional recommendations made by the Advisory Committee. Closing date for comments is 28th July 2009.
Consultation

Photochemical corneal collagen cross-linkage using riboflavin and ultraviolet A for keratoconus (interventional procedures consultation) (30th June 2009)
The National Institute for Health and Clinical Excellence (NICE) is examining photochemical corneal collagen cross-linkage using riboflavin and ultraviolet A for keratoconus and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. NICE’s Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about photochemical corneal collagen cross-linkage using riboflavin and ultraviolet A for keratoconus.

This document summarises the procedure and sets out the provisional recommendations made by the Advisory Committee. Closing date for comments is 28th July 2009.
Consultation

Lateral (including extreme, extra and direct lateral) interbody fusion in the lumbar spine (interventional procedures consultation) (30th June 2009)
The National Institute for Health and Clinical Excellence (NICE) is examining lateral interbody fusion in the lumbar spine and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. NICE’s Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about lateral interbody spinal fusion in the lumbar spine.

This document summarises the procedure and sets out the provisional recommendations made by the Advisory Committee. Closing date for comments is 28th July 2009.
Consultation

Acute coronary syndromes: draft guide consultation (3rd July 2009)
A clinical practice guideline on Acute coronary syndromes is being developed for use in the NHS in England, Wales and Northern Ireland. Registered stakeholders for this guideline are invited to comment on the provisional recommendations. Closing date for comments is 28th August 2009.
Consultation

Corneal endothelial transplantation: Interventional Procedure Guidance IPG304 (24th June 2009)
Some diseases can effect the clear section at the front of the eye (the cornea), and in particular the layers that help maintain its clarity (the endothelium). This procedure aims to replace only the innermost layers of the cornea with a healthy section from a donor eye without disturbing the overall structure of the cornea.
Guidance

Latest Implementation Tools (8th July 2009)
Tools to aid implementation of recently published NICE guidance.

Diarrhoea and vomiting in children: Audit Support and Parental Information Sheet

Glaucoma: Audit Support

Multiple myeloma - lemalidomide: Audit Support and Costing Tool

Head and neck cancer (squamous cell carcinoma) - cetuximab: Audit Support and Costing Tool

Percutaneous endoscopic laser cervical discectomy: Audit Support

NICE

Commissioning Guide - Antenatal and postnatal mental health services (August 2008)
This commissioning guide provides support for the local implementation of NICE clinical guidelines through commissioning, and is a resource to help health professionals in England to commission effective antenatal and postnatal mental health services.
Commissioning Guide

Breast cancer (early and locally advanced): draft guideline consultation (13th August 2008)
A clinical practice guideline on Breast cancer (early & locally advanced) is being developed for use in the NHS in England, Wales and Northern Ireland. Registered stakeholders for this guideline are invited to comment on the provisional recommendations via this website. Closing date for comments is 8th October 2008.
Full Draft Guideline
NICE Draft Guideline
Evidence Review
Needs Assessment
Comments Proforma

Breast cancer (advanced): consultation on the draft guidance (13th August 2008)
A clinical practice guideline on Breast cancer (advanced) is being developed for use in the NHS in England, Wales and Northern Ireland. Registered stakeholders for this guideline are invited to comment on the provisional recommendations via this website. Closing date for comments is 8th October 2008.
Full Draft Guideline
NICE Draft Guideline
Evidence Review
Needs Assessment
Comments Proforma

Promoting Physical Activity for children: consultation on the draft guidance (18th August 2008)
Consultation on the draft guidance relating to Promoting physical activity, active play and sport for pre-school and school age children in family, pre-school, school and community settings. Registered stakeholders are invited to comment on the draft guidance document which entails the draft recommendations. Closing date for comments is 16th September 2008.
Consultation

Management of long-term sickness and absence and incapacity for work: consultation on the draft guidance (20th August 2008)
Consultation on the draft guidance for primary care and employers on the management of long term sickness and incapacity. This consultation will take place between 20 August - 17 September 2008.
Draft Guidance
Comments Form

Insertion of mesh uterine suspension sling (including sacrophysteropexy) for uterine prolapse repair: interventional procedures consultation document (27th August 2008)
The National Institute for Health and Clinical Excellence (NICE) is examining the insertion of mesh uterine suspension sling (including sacrohysteropexy) for uterine prolapse repair and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. NICE's Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about the insertion of mesh uterine suspension sling (including sacrohysteropexy) for uterine prolapse repair. Closing date for comments is 24th September 2008.
Consultation

Infracoccygeal sacropexy using mesh for uterine prolapse repair: interventional procedure consultation document (27th August 2008)
The National Institute for Health and Clinical Excellence (NICE) is examining infracoccygeal sacropexy using mesh for uterine prolapse repair and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. NICE's Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about infracoccygeal sacropexy using mesh for uterine prolapse repair. Closing date for comments is 24th September 2008.
Consultation

Infracoccygeal sacropexy using mesh for vaginal vault prolapse repair: interventional procedure consultation document (27th August 2008)
The National Institute for Health and Clinical Excellence (NICE) is examining infracoccygeal sacropexy using mesh for vaginal vault prolapse repair and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. NICE’s Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about infracoccygeal sacropexy using mesh for vaginal vault prolapse repair. Closing date for comments is 24th September 2008.
Consultation

Sacrocolpopexy using mesh for uterine prolapse repair: interventional procedure consultation document (27th August 2008)
The National Institute for Health and Clinical Excellence (NICE) is examining sacrocolpopexy using mesh for uterine prolapse repair and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. NICE?s Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about sacrocolpopexy using mesh for uterine prolapse repair. Closing date for comments is 24th September 2008.
Consultation

Sacrocolpopexy using mesh for vaginal vault prolapse repair: interventional procedure consultation document (27th August 2008)
The National Institute for Health and Clinical Excellence (NICE) is examining sacrocolpopexy using mesh for vaginal vault prolapse repair and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. NICE?s Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about sacrocolpopexy using mesh for vaginal vault prolapse repair. Closing date for comments is 24th September 2008.
Consultation

Pain (chronic neuropathic or ischaemic) - spinal cord stimulation: final appraisal determination (1st September 2008)
After considering the feedback from consultation, the Appraisal Committee has prepared a Final Appraisal Determination (FAD) on Pain (chronic neuropathic or ischaemic) - spinal cord stimulation and submitted it to the Institute. The FAD has been sent to the formal consultees for this appraisal who have 15 working days to consider whether they wish to appeal against it. Subject to any appeal by consultees, the FAD may be used as the basis for the Institute's guidance on the use of the appraised technology in the NHS in England and Wales. Please note that the appeal period for this appraisal will close at 5pm on 15th September 2008.
Final Appraisal Determination
Table of comments on ACD
Consultee and Commentator Comments
Expert Comments on the ACD

Abdominal aortic aneurysm - endovascular stent-grafts: appraisal consultation (2nd September 2008)
The Department of Health has asked the National Institute for Health and Clinical Excellence (NICE or the Institute) to conduct a multiple technology appraisal of endovascular stent–grafts and provide guidance on their use to the NHS in England. The Appraisal Committee has had its first meeting to consider both the evidence submitted and the views put forward by non-manufacturer consultees and commentators, and by the clinical specialist and patient expert representatives nominated for this appraisal by non-manufacturer consultees and commentators. The Committee has developed preliminary recommendations on the use of endovascular stent–grafts. Closing date for comments is 22nd September 2008.
Consultation
Evaluation Report

Hearing impairment - cochlear implants: final appraisal determination (2nd September 2008)
After considering the feedback from consultation, the Appraisal Committee has prepared a Final Appraisal Determination (FAD) on Cochlear implants for severe to profound deafness in children and adults and submitted it to the Institute. The FAD has been sent to the formal consultees for this appraisal who have 15 working days to consider whether they wish to appeal against it. Subject to any appeal by consultees, the FAD may be used as the basis for the Institute's guidance on the use of the appraised technology in the NHS in England and Wales. Please note that the appeal period for this appraisal will close at 5pm on 16 September 2008.
Final Appraisal Determination
Response to Consultee, Commentator and Public Comments on the ACD
Consultee and Commentator Comments on the ACD
Expert comments on the ACD

Identification and management of familial hypercholesterolaemia Clinical Guideline CG71 (27th August 2008)
The advice in the NICE guideline covers the care and treatment of adults and children/young people with familial hypercholesterolaemia (a specific type of inherited high cholesterol that runs in the family). It does not cover other forms of hypercholesterolaemia that are not genetic (inherited) or that are due to other genetic conditions.
Full Guideline and Appenices A - G
NICE Guideline
Quick Reference Guide
Understanding NICE Guidance
Costing Template
Costing Report

Entecavir for the treatment of chronic hepatitis B Technology Appraisal TA153 (27th August 2008)
Entecavir is recommended as a possible treatment for people with chronic hepatitis B.
Guidance
Quick Reference Guide
Understanding NICE Guidance
Costing Statement
Audit Support

Telbivudine for the treatment of chronic hepatitis B Technology Appraisal TA154 (27th August 2008)
Telbivudine is not recommended for people with chronic hepatitis B. Healthcare professionals should not stop prescribing telbivudine for people who were already taking it when the guidance was issued. These patients should be able to carry on taking telbivudine until they and their healthcare professionals decide that it is the right time to stop treatment.
Guidance
Quick Reference Guide
Understanding NICE Guidance
Audit Support
Costing Statement

Implantation of miniature lens systems for advanced age-related macular degeneration Interventional Procedure Guidance IPG272 (27th August 2008)
Age-related macular degeneration is an eye disorder that usually starts later in life and causes problems with central vision. In this procedure, a combination of artificial lenses is implanted behind the pupil of one eye. The aim is that the implanted lenses help improve central vision while the other eye is used for peripheral vision.
Guidance
Understanding NICE Guidance
Audit Support
Consultation Comments

Macular degeneration (age-related) - ranibizumab and pegaptanib Technology Appraisal TA155 (27th August 2008)
Ranibizumab is recommended as a possible treatment for people with wet AMD if all the following apply to their eye: The best possible visual acuity after correction with glasses or contact lenses is between 6/12 and 6/96; There is no permanent damage to the fovea (the part of the eye that helps people to see things in sharp detail); The area affected by AMD is no larger than 12 times the size of the area inside the eye where the optic nerve connects to the retina; and There are signs that the condition has been getting worse. Pegaptanib is not recommended for people with wet AMD. Healthcare professionals should not immediately stop prescribing pegaptanib for people who were already taking it when the guidance was issued. These people should be able to carry on taking pegaptanib until they and their healthcare professionals decide that it is the right time to stop treatment.
Guidance
Quick Reference Guide
Understanding NICE Guidance
Cost Template

Pregnancy (rhesus negative women) - routine anti-D (review) (27th August 2008)
Routine antenatal anti-D prophylaxis is recommended as a treatment option for all pregnant women who are RhD negative and who are not known to be 'sensitised'. When a decision has been made to give routine antenatal anti-D prophylaxis, the treatment with the lowest cost should be used. This should take into account the costs of both obtaining and giving the treatment.
Guidance
Quick Reference Guide
Understanding NICE Guidance
Audit Support
Costing Statement

Technical patient safety solutions for ventilator - associated pneumonia in adults Patient Safety Solutions Pilot Guidance PSG002 (27th August 2008)
The NICE guidance covers patients who are on a ventilator and have a tube placed into their mouth, nose or through the neck and down into their windpipe. Healthcare professionals should: make sure these patients are sitting up or leaning back supported for as much of the time as possible. This will not be appropriate for all patients (for example, those with injuries to the spine); and make sure an antiseptic is included as part of the mouth care routine for these patients.
Guidance
Understanding NICE Guidance
Costing Statement
Audit Support
Slide Set

Total Wrist Replacement Interventional Procedure Guidance IPG271 (27th August 2008)
Arthritis is a condition that causes swelling and damage to the cartilage and bone around the joints, including the wrist. It is painful and can reduce the function of the joint. Total wrist replacement aims to create an artificial wrist joint consisting of metal implants attached to the end of the arm and to the hand, separated by a spacer to allow movement of the hand.
Guidance
NICE Guidance

NICE

Multiple myeloma - lenalidomide: final appraisal determination (23rd April 2009)
After considering the feedback from consultation, the Appraisal Committee has prepared a Final Appraisal Determination (FAD) on lenalidomide for multiple myeloma in people who have received at least one prior therapy and submitted it to the Institute. The FAD has been sent to the formal consultees for this appraisal who, for this appraisal, have 20 working days to consider whether they wish to appeal against it. Subject to any appeal by consultees, the FAD may be used as the basis for the Institute's guidance on the use of the appraised technology in the NHS in England and Wales. Closing date for comments is 15th May 2009.
FAD

Extracorporeal shockwave therapy for refractory tennis elbow: interventional procedures consultation (25th April 2009)
NICE has reviewed the guidance on extracorporeal shockwave therapy for refractory tendinopathies (plantar fasciitis and tennis elbow) (IPG139, November 2005) and is reassessing the procedure separately for plantar fasciitis, tennis elbow (see below) and Achilles tendinopathy. New guidance will be published as a result. Until the new guidance is published the NHS should continue to follow the current recommendations.

The Interventional Procedures Advisory Committee has considered this procedure and NICE has now issued a consultation document about its safety and efficacy. This has been issued for 4 weeks public consultation (until 5pm on 26 may 2009).
Consultation

Percutaneous intradiscal elecrothermal therapy for lower back pain: interventional procedures consultation (25th April 2009)
The Interventional Procedures Advisory Committee has considered this procedure and NICE has now issued a consultation document about its safety and efficacy. This has been issued for 4 weeks public consultation (until 5pm on 26 may 2009).
Consultation

Extracorporeal shockwave therapy for refractory Achilles tendinopathy: interventional procedures consultation (25th April 2009)
NICE has reviewed the guidance on extracorporeal shockwave therapy for refractory tendinopathies (plantar fasciitis and tennis elbow) (IPG139, November 2005) and is reassessing the procedure separately for plantar fasciitis, tennis elbow and Achilles tendinopathy (see below). New guidance will be published as a result. Until the new guidance is published the NHS should continue to follow the current recommendations.

The Interventional Procedures Advisory Committee has considered this procedure and NICE has now issued a consultation document about its safety and efficacy. This has been issued for 4 weeks public consultation (until 5pm on 26 may 2009).
Consultation

Extracorporeal shockwave therapy for refractory plantar fasciitis: interventional procedures consultation (25th April 2009)
The National Institute for Health and Clinical Excellence (NICE) has issued full guidance to the NHS in England, Wales, Scotland and Northern Ireland on extracorporeal shock wave therapy for refractory tendinopathies (plantar fasciitis and tennis elbow) in November 2005.

NICE has reviewed the guidance on extracorporeal shockwave therapy for refractory tendinopathies (plantar fasciitis and tennis elbow) (IPG139, November 2005) and is reassessing the procedure separately for plantar fasciitis (see below), tennis elbow and Achilles tendinopathy. New guidance will be published as a result. Until the new guidance is published the NHS should continue to follow the current recommendations.
Consultation

Placement of pectus bar for pectus excavatum (Nuss procedure) (25th April 2009)
The Interventional Procedures Advisory Committee has considered this procedure and NICE has now issued a consultation document about its safety and efficacy. This has been issued for 4 weeks public consultation (until 5pm on 26 May 2009).

Pectus excavatum is an abnormality of the chest in which the breastbone sinks inward (sometimes called funnel chest). Problems associated with pectus excavatum are mainly cosmetic, although the condition can impair cardiac and respiratory function. Placement of a pectus bar for pectus excavatum (also known as the Nuss procedure) involves placing one or two steel (pectus) bars under the breastbone with the aim of raising it and correcting the abnormal shape. The bar, which is bent into a curve to fit the patient’s chest, is inserted through small openings in the chest. The bar (or bars) are usually removed within a few years of placement.
Consultation

Ultrasound-guided foam sclerotherapy for varicose veins: interventional procedures consultation (25th April 2009)
The National Institute for Health and Clinical Excellence (NICE) issued full guidance to the NHS in England, Wales, Scotland and Northern Ireland on ultrasound-guided foam sclerotherapy for varicose veins in May 2007. This replaced the previous guidance on 'Ultrasound guided foam sclerotherapy for varicose veins' (Interventional Procedures Guidance no. 182, June 2006).

The Interventional Procedures Advisory Committee has considered this procedure and NICE has now issued a consultation document about its safety and efficacy. This has been issued for 4 weeks public consultation (until 5pm on 26 may 2009).
Consultation

Eczema (chronic) - alitretinoin: appraisal consultation (30th April 2009)
The Department of Health has asked the National Institute for Health and Clinical Excellence (NICE or the Institute) to conduct a single technology appraisal (STA) of alitretinoin for the treatment of severe chronic hand eczema and provide guidance on its use to the NHS in England and Wales. The Appraisal Committee has had its first meeting to consider both the evidence submitted by the manufacturer and the views put forward by non-manufacturer consultees and commentators, and by the clinical specialist and patient expert representatives nominated for this appraisal by non-manufacturer consultees and commentators. The Committee has developed preliminary recommendations on the use of alitretinoin for the treatment of severe chronic hand eczema. Closing date for comments is 20th May 2009.
Consultation

School-based interventions to prevent smoking: consultation on the evidence (1st May 2009)
NICE was asked by the Department of Health (DH) to develop public health intervention guidance on School-based interventions to prevent the uptake of smoking amongst children. Closing date for comments is 3rd June 2009.
Consultation

Reducing differences in uptake of immunisations: additional evidence consultation (5th May 2009)
NICE was asked by the Department of Health (DH) to develop public health intervention guidance to reduce differences in the uptake of immunisations (including targeted vaccines) in children and young people aged under 19 years. Closing date for comments is 2nd June 2009.
Consultation

Reducing differences in uptake of immunisations: draft guidance consultation (5th May 2009)
NICE is developing public health intervention guidance on differences in the uptake of immunisations (including targeted vaccines) in children and young people aged under 19 years. Closing date for comments is 2nd June 2009.
Consultation

Hepatocellular carcinoma (advanced and metastatic) - sorafenib (first line): appraisal consultation (7th May 2009)
The Department of Health has asked the National Institute for Health and Clinical Excellence (NICE or the Institute) to conduct a single technology appraisal (STA) of sorafenib for the treatment of hepatocellular carcinoma and provide guidance on its use to the NHS in England and Wales. The Appraisal Committee has had its first meeting to consider both the evidence submitted by the manufacturer and the views put forward by non-manufacturer consultees and commentators, and by the clinical specialist and patient expert representatives nominated for this appraisal by non-manufacturer consultees and commentators. The Committee has developed preliminary recommendations on the use of sorafenib for the treatment of hepatocellular carcinoma. Closing date for comments is 29th May 2009.
Consultation

Prevention of cardiovascular disease: consultation on the evidence (12th May 2009)
NICE was asked by the Department of Health (DH) to develop guidance on the prevention of cardiovascular disease at the population level. Closing date for comments is 12th June 2009.
Consultation

Latest Implementation Tools (13th May 2009)
Tools to aid implementation of recently published guidance

Diabetes type 2 (new drugs update): Costing tool

Diarrhoea and vomiting in children: Costing tool and Slide set

Glaucoma: Costing tool and Slide set

Breast cancer (advanced): Audit support and Guide to resources

Breast cancer (early): Audit support

Rheumatoid arthritis in adults: Audit support

Venous thromboembolism - rivaroxaban: Audit support and Costing tool

Needle and syringe programmes: Local authority planning committee checklist, Factsheet for commissioners and Audit support

Combined bony and soft tissue reconstruction for hip joint stabilisation in proximal focal femoral deficiency: Audit support

Ex-vivo hepatic resection and reimplantation for liver cancer: Audit support

NICE

Balloon catheter dilation of paranasal sinus ostia for chronic sinusitis (interventional procedures consultation) (2nd January 2008)
Sinusitis occurs when air-filled cavities of the face (the sinuses) become inflamed. Balloon catheter dilation aims to keep sinus passages open by gently inflating a small balloon, which is introduced through the nose via a flexible tube. The National Institute for Health and Clinical Excellence is examining balloon catheter dilation of paranasal sinus ostia for chronic sinusitis and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. The Institute's Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about balloon catheter dilation of paranasal sinus ostia for chronic sinusitis. Closing date for comments is 30th January 2008.
Click here for the Consultation

Interstitial photodynamic therapy for malignant parotid tumours (interventional procedures consultation) (2nd January 2008)
The parotid glands are located in front of the ears and help to produce saliva. Rarely, they may be affected by malignant tumours. In photodynamic therapy (usually abbreviated to PDT), a drug called a 'photosensitising agent' is injected into a vein. A few days later, special needles and fibres are inserted into the tumour and a special light is shone through them. The light causes the photosensitising agent to destroy the tumour cells. The National Institute for Health and Clinical Excellence is examining interstitial photodynamic therapy for malignant parotid tumours and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. The Institute's Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about interstitial photodynamic therapy for malignant parotid tumours. Closing date for comments is 30th January 2008.
Click here for the Consultation

Endoaortic balloon occlusion for cardiac surgery (interventional procedures consultation) (2nd January 2008)
During major heart surgery, the flow of blood through the heart needs to be stopped temporarily. In endoaortic balloon occlusion, a flexible tube (catheter) with a balloon attached to its tip is inserted into an artery in the groin (femoral artery) and threaded up to the heart. When the catheter is in the correct position in the heart, the balloon is filled with saline. As the balloon expands it blocks the aorta, which is the largest artery in the body. With the aorta blocked, the heart surgery can be performed. After heart surgery, the balloon and catheter are removed and the blood flow is restored. The National Institute for Health and Clinical Excellence is examining endoaortic balloon occlusion for cardiac surgery and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. The Institute's Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about endoaortic balloon occlusion for cardiac surgery. Closing date for comments is 30th January 2008.
Click here for the Consultation

Intraoperative red blood cell salvage during radical prostatectomy or radical cystectomy (interventional procedures consultation) (2nd January 2008)
Intraoperative red blood cell salvage involves the collection of the solid components of the blood lost during an operation, which are then transfused back to the same patient. The National Institute for Health and Clinical Excellence is examining intraoperative red blood cell salvage during radical prostatectomy or radical cystectomy and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. The Institute's Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about intraoperative red blood cell salvage during radical prostatectomy or radical cystectomy. Closing date for comments is 30th January 2008.
Click here for the Consultation

Allogeneic pancreatic islet cell transplantation for type 1 diabetes mellitus (interventional procedures consultation) (2nd January 2008)
Type 1 diabetes mellitus occurs when the body does not produce enough insulin (a substance that helps control sugar balance in the body). Although treatable with insulin injections, it is associated with an increased risk of other health problems, such as vascular disease. Allogeneic pancreatic islet cell transplantation involves the removal of islet cells, which are responsible for the production of insulin, from human donors. These cells are inserted into the patient's liver to restart insulin production within the body. Patients who have this procedure take medications so their body's immune system does not reject the cells. It is associated with some serious risks and is only considered in special circumstances. The National Institute for Health and Clinical Excellence is examining allogeneic pancreatic islet cell transplantation for type 1 diabetes mellitus and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. The Institute's Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about allogeneic pancreatic islet cell transplantation for type 1 diabetes mellitus. Closing date for comments is 30th January 2008.
Click here for the Consultation

Workplace Physical Activity: consultation on the draft guidance (21st December 2007)
NICE was asked by the Department of Health to develop intervention guidance on workplace health promotion with reference to physical activity. All registered stakeholders for the NICE public health intervention guidance on Workplace Physical Activity are invited to comment on the draft guidance. This consultation will take place between Friday 21st December 2007 and Friday 25th January 2008.
Click here for the Draft Guidance
Click here for the Comments Form

Schizophrenia (update) (21st December 2007)
The scope defines what aspects of care are covered by the guideline and to whom it applies. Comments that were made by stakeholders during the consultation on the scope can be seen in the scope consultation table.
Click here for the Final Scope
Click here for the Consultation Table

NICE

New database to inform prioritisation of European cancer research (20th October 2009)
A 'Database of Cancer Uncertainties' (DoCU) went live on the NICE website today. The database will collate details of the major gaps in evidence which are identified during guidance development. These evidence gaps can then be promoted as research priorities to prospective research funders.

The database has been developed as a pilot project by NICE, as part of the CoCanCPG (Coordination of Cancer Clinical Practice Guidelines in Europe). CoCanCPG is a consortium of 16 institutional partners from 11 countries.
Database

What do you think about the NICE website? (27th October 2009)
As part of their continuing programme of evaluation and development, NICE are currently consulting with health service and local government professionals, patients, carers and the public to find out what they think of the NICE website.

The survey is available online until 15th November 2009.
Survey

Neuropathic pain - pharmacological management: guideline consultation (14th October 2009)
A clinical practice guideline on Neuropathic pain is being developed for use in the NHS in England, Wales and Northern Ireland. Registered stakeholders for this guideline are invited to comment on the provisional recommendations via this website.

Closing date for comments is 11th November 2009
Consultation

Prevention of cardiovascular disease: additional evidence consultation (14th October 2009)
NICE was asked by the Department of Health (DH) to develop public health programme guidance on preventing cardiovascular disease (CVD) in different populations.

All registered stakeholders are now invited to comment on the economic analysis and additional evidence that has been assembled to inform the development of this guidance. This will be used by the Programme Development Group (PDG) to develop recommendations.

Closing date for comments is 16th November 2009.
Consultation

Prevention of cardiovascular disease: consultation on the draft guidance (15th October 2009)
NICE are consulting on the draft guidance ‘prevention of cardiovascular disease at the population level’. In particular, they are interested in the views of stakeholders on recommendations 3, 4 and 5 (on salt, saturated fats and trans fats). They are interested in views on:

• Whether a figure for a lower target for salt intake could or should be identified at this stage
• Whether an even lower saturated fat intake is achievable
• The potential impact of a ban on industrial trans fats on cardiovascular disease in general and particularly the potential effects on existing inequalities in health.

NICE also welcome comments about other recommendations and sections of the guidance. Closing date for comments is 16th November 2009.
Consultation

Rheumatoid arthritis - certolizumab pegol: appraisal consultation (20th October 2009)
This appraisal consultation on Rheumatoid arthritis - certolizumab pegol, is open for comments until 10th November 2009. All registered stakeholders are invited to comment.
Consultation

Breast cancer (advanced or metastatic) - lapatinib: appraisal consultation document (21st October 2009)
The Department of Health and the Welsh Assembly Government have asked the National Institute for Health and Clinical Excellence (NICE) to produce guidance on using lapatinib for the treatment of women with previously treated advanced or metastatic breast cancer in the NHS in England and Wales. The Appraisal Committee has considered the evidence submitted by the manufacturer and the views of non-manufacturer consultees and commentators, and clinical specialists and patient experts.

Closing date for comments is 11th November 2009.
Consultation

Cytoreduction surgery followed by hyperthermic intraoperative peritoneal chemotherapy for peritoneal carcinomatosis (interventional procedures consultation) (21st October 2009)
The National Institute for Health and Clinical Excellence (NICE) is examining cytoreduction surgery followed by hyperthermic intraoperative peritoneal chemotherapy for peritoneal carcinomatosis and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. NICE’s Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about cytoreduction surgery followed by hyperthermic intraoperative peritoneal chemotherapy for peritoneal carcinomatosis.

Closing date for comments is 18th November 2009.
Consultation

Therapeutic endoscopic division of epidural adhesions (interventional procedures consultation) (21st October 2009)
The National Institute for Health and Clinical Excellence (NICE) is examining therapeutic endoscopic division of epidural adhesions and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. NICE’s Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about therapeutic endoscopic division of epidural adhesions.

Closing date for comments is 18th November 2009.
Consultation

Surgical correction of hallux valgus using minimal access techniques (interventional procedures consultation) (21st October 2009)
Hallux valgus is a deformity of the big toe. The big toe tilts outwards, crowding the smaller toes, and a bony lump (called a bunion) appears on the inside of the foot.

The National Institute for Health and Clinical Excellence (NICE) is examining surgical correction of hallux valgus using minimal access techniques and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. NICE’s Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about surgical correction of hallux valgus using minimal access techniques.

Closing date for comments is 18th November 2009.
Consultation

Selective internal radiation therapy for colorectal metastases in the liver (interventional procedures consultation) (21st October 2009)
Colorectal liver metastasis is cancer that has spread to the liver from the bowel. Selective internal radiation therapy (known as SIRT) uses radiation put into the patient’s liver to kill the cancer cells. Tiny radioactive ‘beads’ are injected into the artery that supplies blood to the liver (the hepatic artery). The beads become trapped (embolise) in the tiny blood vessels surrounding the cancer, releasing radiation directly onto it. The treatment may be repeated.

The National Institute for Health and Clinical Excellence (NICE) is examining selective internal radiation therapy for colorectal metastases in the liver and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. NICE’s Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about selective internal radiation therapy for colorectal metastases in the liver.

Closing date for comments is 18th November 2009.
Consultation

Prosthetic intervertebral disc replacement in the cervical spine (interventional procedures consultation)(21st October 2009)
Bulging of a disc (called herniation) in the neck occurs when one or more of the spinal discs between the bones in the neck bursts and pushes against the spinal cord or nerve roots that run through the backbone. This herniation can cause pain in the neck, or pain, weakness and numbness in the arms and legs.

This procedure involves replacing damaged discs in the neck with artificial ones designed to act like natural neck discs.

The National Institute for Health and Clinical Excellence (NICE) is examining prosthetic intervertebral disc replacement in the cervical spine and will publish guidance on its safety and efficacy to the NHS in England, Wales, Scotland and Northern Ireland. NICE’s Interventional Procedures Advisory Committee has considered the available evidence and the views of Specialist Advisers, who are consultants with knowledge of the procedure. The Advisory Committee has made provisional recommendations about prosthetic intervertebral disc replacement in the cervical spine.

Closing date for comments is 18th November 2009.
Consultation

Venous thromboembolism - reducing the risk: pre-publication check (22nd October 2009)
Following two consultation periods on the provisional recommendations, the National Clinical Guidelines Centre for Acute and Chronic Conditions (NCGC) and the Guideline Development Group (GDG) for Venous thromboembolism – reducing the risk, have considered and responded to stakeholder comments and amended the draft guideline.

The revised full guideline is now available on the web for a pre-publication check of factual errors. This is still draft guidance and has not been sent out to the NHS. The pre-publication check is not an additional consultation or an opportunity to reopen arguments and issues highlighted during consultation on the draft guidelines. The GDG will already have considered these issues in forming the recommendations contained in the draft for the pre-publication check.

Registered stakeholders for this guideline are invited to report any factual errors in the guideline by 11th November 2009.
Pre-publication check

Weight management in pregnancy: consultation on the evidence (22nd October 2009)
NICE was asked by the Department of Health (DH) to develop guidance on ‘Dietary interventions and physical activity interventions for weight management in pregnancy’.

All registered stakeholders are now invited to comment on the evidence that has been assembled to inform the development of this guidance. This evidence will be used by the Public Health Interventions Advisory Committee (PHIAC) to develop draft recommendations. The evidence comprises a review of effectiveness an economic analysis.

Closing date for comments is 19th November 2009.
Consultation

Bacterial meningitis and meningococcal septicaemia in children: guideline consultation (22nd October 2009)
A clinical practice guideline on Bacterial meningitis and meningococcal septicaemia in children is being developed for use in the NHS in England, Wales and Northern Ireland. Registered stakeholders for this guideline are invited to comment on the provisional recommendations.

Closing date for comments is 17th December 2009.
Consultation

Strategies to prevent unintentional injuries among under 15s: consultation on the evidence (26th October 2009)
NICE was asked by the Department of Health (DH) to ‘Prepare public health programme guidance on the prevention of unintentional injury in children under 15’.

All registered stakeholders are now invited to comment on the evidence that has been assembled to inform the development of this guidance. This evidence is used by the Programme Development Group (PDG) to develop draft recommendations.

Closing date for comments is 23rd November 2009.
Consultation

Technology Appraisal TA182. Prasugrel for the treatment of acute coronary syndromes with percutaneous coronary intervention (28th October 2009)
Prasugrel in combination with aspirin is recommended as an option for preventing blockages in the arteries of people with acute coronary syndromes who are having a treatment called percutaneous coronary intervention only when:

• immediate percutaneous coronary intervention is necessary to treat an ST-segment-elevation myocardial infarction (a type of heart attack) or
• a blood clot has blocked a stent (a small mesh-like tube inserted into an artery to keep it open) during treatment with a drug called clopidogrel or
• the patient has diabetes mellitus.

Guideline

Technology Appraisal TA183. Topotecan for the treatment of recurrent carcinoma of the cervix (28th October 2009)
Topotecan in combination with cisplatin is recommended as a possible treatment for women with recurrent or stage IVB cervical cancer only if they have not received cisplatin before. Healthcare professionals should not stop prescribing topotecan for women who have received cisplatin before and who were already taking topotecan with cisplatin when the guidance was issued. These women should be able to carry on taking topotecan until they and their healthcare professionals decide that it is the right time to stop treatment.
Guideline

Clinical Guideline CG90. Depression: the treatment and management of depression in adults (update) (28th October 2009)
This guideline is published alongside ‘Depression in adults with a chronic physical health problem: treatment and management’ (NICE clinical guideline 91), which makes recommendations on the identification, treatment and management of depression in adults aged 18 years and older who also have a chronic physical health problem.
Guideline

Clinical Guideline CG91. The treatment and management of depression in adults with chronic physical health problems (partial update of CG23)
This guideline is published alongside ‘Depression: the treatment and management of depression in adults (update)’ (NICE clinical guideline 90), which makes recommendations on the identification, treatment and management of depression in adults aged 18 years and older, in primary and secondary care.

This guideline (and CG90) update recommendations made in NICE technology appraisal guidance 97 for the treatment of depression only. The guidance in TA97 remains unchanged for the use of CCBT in the treatment of panic and phobia and obsessive compulsive disorder.
Guideline

NICE

Ovarian cancer: draft scope consultation (18th February 2009)
NICE have been asked to develop a clinical practice guideline on Ovarian Cancer for use in the NHS in England, Wales and Northern Ireland. The draft scope defines what aspects of care the guideline will cover and to whom it will apply. Closing date for comments is 18th March 2009.
Consultation

Colorectal cancer: draft scope consultation (18th February 2009)
NICE have been asked to develop a clinical practice guideline on Colorectal Cancer for use in the NHS in England, Wales and Northern Ireland. The draft scope defines what aspects of care the guideline will cover and to whom it will apply. Closing date for comments is 18th March 2009.
Consultation

Promoting young people's social and emotional wellbeing in secondary education: guidance consultation (18th February 2009)
NICE is developing public health intervention guidance promoting social and emotional wellbeing in secondary education. Closing date for comments is 18th March 2009.
Consultation

Hysteroscopic sterilisation by tubal cannulation and placement of intrafallopian implant (24th February 2009)
NICE has reviewed this guidance that was published in August 2004 and is reassessing the procedure. Closing date for comments is 24th February 2009.
Consultation

Corneal endothelial transplantation (24th February 2009)
The Interventional Procedures Advisory Committee has considered this procedure and NICE has now issued a consultaion document about its safety and efficacy. Closing date for comments is 24th March 2009.
Consultation

Insertion of individually magnetic resonance imaging designed unicompartmental interpositional implant in osteorthritis of the knee (24th February 2009)
The Interventional Procedures Advisory Committee has considered this procedure and NICE has now issued a consultation document about its safety and efficacy. Closing date for comments is 24th March 2009.
Consultation

Percutaneous endoscopic laser cervical discectomy (24th February 2009)
NICE has reveiwed this guidance that was published in June 2004 and has now issued a consultation document about its safety and efficacy. Closing date for comments is 24th March 2009.
Consultation

Percutaneous mitral valve leaflet repair for mitral regurgitation (24th February 2009)
The Interventional Procedures Advisory Committee reconsidered this procedure in light of comments received during the initial consultation in January 2009. Nice have now issued a second consultation document about its safety and efficacy. Closing date for comments is 24th March 2009.
Consultation

Depression in adults (update): draft guideline consultation (24th February 2009)
A clinical practice guideline on Depression in adults (update) is being developed for use in the NHS in England, Wales and Northern Ireland. Closing date for comments is 21st April 2009.
Consultation

Endovascular stent - grafts for the treatment of abdominal aortic aneuryms Technology appraisal TA167 (25th February 2009)
Endovascular stent-grafts are recommended as a possible treatment for people with abdominal aortic aneurysms if:

• the aneurysm is below their kidney and has not burst
• surgery is appropriate, and
• the person and their specialist have decided the risks and benefits of this and other procedures and decided that endovascular stent-grafts are appropriate

Guidance

Amantadine, oseltamivir and zanamivir for the treatment of influenza (review of existing guidance No. 58) Technology appraisal TA168 (25th February 2009)
NICE has said that its receommendations about oseltamivir and zanamivir should not reduce efforts to give vaccination to people for whom it is recommended in national guidelines. The guidance does not cover widespread epidemics.
Guidance

Advanced breast cancer: diagnosis and treatment Clinical guideline CG81 (25th February 2009)
This guidance updates and replaces NICE technology appraisal guidance 63 (published May 2003), 54 (published December 2002) and 30 (published September 2001). The advice in the NICE guideline describes the tests, treatment, care and support that patients with advanced breast cancer should be offered. It does not specifically describe the care of patients with early breast cancer or those with rare or non-cancerous tumours of the breast.
Guidance

Early and locally advanced breast cancer: diagnosis and treatment Clinical guideline CG80 (25th February 2009)
The advice in this guideline covers some of the tests and treatments that patients with early and locally advanced breast cancer should be offered, in particular:

• reducing the amount of surgery under your arm
• breast reduction when breast conservation is not possible
• chemotherapy and endocrine treatments
• biological treatments

Guidance

Rheumatoid arthritis: the management of rheumatoid arthritis in adults Clinical guideline CG79 (25th February 2009)
The advice in the NICE guideline covers the care of adults with rheumatoid arthritis. It does not specifically look at other types of arthritis such as osteoarthritis.
Guidance

Extracorporeal photopheresis for Crohn's disease Interventional procedures guidance IPG288 (25th February 2009)
Crohn's disease is a chronic inflammatory disease that affects the gastrointestinal tract. It is sometimes associated with other complications such as skin rashes and arthritis. In extracorporeal photopheresis blood is removed from the patient, then the white blood cells are separated from the whole blood, treated with ultraviolet light and re-infused into the patient.
Guidance

Intraocular lens insertion for correction of refractive error, with preservation of the natural lens Interventional procedure guidance IPG289 (25th February 2009)
Short-sightedness is the inability to see clearly at a distance. Eyesight can usually be corrected by wearing spectacles or contact lenses. Insertion of a clear plastic lens in front of the existing lens is a procedure that aims to improve vision in short-sightedness.
Guidance

Laparoscopic cystectomy Interventional procedure guidance IPG287 (25th February 2009)
This procedure is used to treat:

• invasive bladder carcinoma
• ongoing incontinence due to paraplegia, where catheterisation results in infection and ongoing leakage
• refractory complications in a defunctionalized bladder, where urinary diversion is already established

Guidance

Needle and syringe programmes: providing people who inject drugs with injecting equipment Public health guidance PH18 (25th February 2009)
The recommendations relate to people over the age of 18 who inject illicit substances and non-prescribed anabolic steroids. The guidance complements and supports, but does not replace NICE guidance on drug and substance misuse.
Guidance

Commissioning Guides (February 2009)
NICE have published 2 new commissioning guides:

• Insuline Pump Therapy Service

and

• Service for the diagnosis and management of ADHD in adults

Consultation on the Topic Selection Process for Technology Appraisals (2nd March 2009)

This consultation document seeks views on some proposed changes to the way in which technology appraisal topics are selected for referral to the National Institute for Health and Clinical Excellence (NICE). Closing date for comments is 22nd May 2009.
Consultation

Venous thromboembolism - reducing the risk: guideline consultation (2nd March 2009)
A clinical practice guideline on venous thromboembolism – reducing the risk is being developed for use in the NHS in England, Wales and Northern Ireland. Registered stakeholders for this guideline are invited to comment on the provisional recommendations. Closing date for comments is 27th April 2009.
Consultation

Depression in chronic health problems: draft guideline consultation (3rd March 2009)
A clinical practice guideline on Depression in chronic health problems is being developed for use in the NHS in England, Wales and Northern Ireland. Registered stakeholders for this guideline are invited to comment on the provisional recommendations. Closing date for comments is 28th April 2009.
Consultation

Breast cancer (advanced or metastatic) - lapatinib: final appraisal determination (5th March 2009)
After considering the feedback from consultation, the Appraisal Committee has prepared a Final Appraisal Determination (FAD) on Lapatinib for breast cancer (for use in women with previously treated advanced or metastatic breast cancer) and submitted it to the Institute.

The FAD has been sent to the formal consultees for this appraisal who have 15 working days to consider whether they wish to appeal against it. Subject to any appeal by consultees, the FAD may be used as the basis for the Institute's guidance on the use of the appraised technology in the NHS in England and Wales. The appeal period will close on 27th March 2009.
FAD

Venous thromboembolism - rivaroxaban: final appraisal determination (5th March 2009)
After considering the feedback from consultation, the Appraisal Committee has prepared a Final Appraisal Determination (FAD) on rivaroxaban for the prevention of venous thromboembolism and submitted it to the Institute.

The FAD has been sent to the formal consultees for this appraisal who have 15 working days to consider whether they wish to appeal against it. Subject to any appeal by consultees, the FAD may be used as the basis for the Institute's guidance on the use of the appraised technology in the NHS in England and Wales. The appeal period will close on 27th March 2009.
FAD

Gastrointestinal stromal tumours - sunitinib: appraisal consultation (5th March 2009)
The Department of Health has asked the National Institute for Health and Clinical Excellence (NICE or the Institute) to conduct a single technology appraisal (STA) of sunitinib for the treatment of gastrointestinal stromal tumours and provide guidance on its use to the NHS in England and Wales. The Appraisal Committee has had its first meeting to consider both the evidence submitted by the manufacturer and the views put forward by non-manufacturer consultees and commentators, and by the clinical specialist and patient expert representatives nominated for this appraisal by non-manufacturer consultees and commentators. The Committee has developed preliminary recommendations on the use of sunitinib for the treatment of gastrointestinal stromal tumours. Closing date for comments is 26th March 2009.
Consultation

Hepatitis B - tenofovir disoproxil fumarate: appraisal consultation (5th March 2009)
The Department of Health asked the National Institute for Health and Clinical Excellence (NICE or the Institute) to conduct a single technology appraisal (STA) of tenofovir disoproxil for the treatment of chronic hepatitis B and provide guidance on its use to the NHS in England and Wales. The Appraisal Committee has had its first meeting to consider both the evidence submitted by the manufacturer and the views put forward by non-manufacturer consultees and commentators, and by the clinical specialist and patient expert representatives nominated for this appraisal by non-manufacturer consultees and commentators. The Committee has developed preliminary recommendations on the use of tenofovir disoproxil for the treatment of chronic hepatitis B. Closing date for comments is 26th March 2009.
Consultation

Providing public information to prevent skin cancer: consultation on the evidence (6th March 2009)
NICE was asked by the Department of Health (DH) to develop public health intervention guidance for the NHS and local authorities on the prevention of skin cancer in the general public with specific reference to:

• provision of information
• physical changes to the environment
• supply of sun protection resources

Registered stakeholders are now invited to comment on the evidence that has been assembled to inform the development of the first piece of guidance (Provision of information). Closing date for comments is 3rd April 2009.
Consultation

Psychosis with substance misuse: scope consultation (10th March 2009)
NICE have been asked to develop a clinical practice guideline on Psychosis with substance abuse for use in the NHS in England, Wales and Northern Ireland. The draft scope defines what aspects of care the guideline will cover and to whom it will apply. Registered stakeholders for this guideline are invited to submit comments on the scope and may suggest clinical questions that could be answered in the guideline. Closing date for comments is 7th April 2009.
Consultation

Latest implementation tools (11th March 2009)
Tools to aid implementation of recently published guidance.

Breast cancer - early: Costing tool and Slide set

Breast cancer - advanced: Costing tool and Slide set

Rheumatoid arthritis in adults: Costing tool

Influenza (treatment) zanamivir, amantadine and oseltamivir: Costing tool and Audit Support

Abdominal aortic aneurysms - endovascular stent-grafts: Costing tool and Audit Support

Needle and syringe programmes: Slide set